Recurrent Postural Vasovagal Syncope: Sympathetic Nervous System Phenotypes Running title: Vaddadi et al.; Sympathetic function in Vasovagal Syncope
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چکیده
Diab b b b b b bet et et et et et etes es es es es es s I I I I I I Ins ns ns ns ns ns nsti ti ti ti ti ti titu tu tu tu tu tu tute y, Abstract: Background-The pathophysiology of vasovagal syncope (VVS) is poorly understood and the
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Recurrent postural vasovagal syncope: sympathetic nervous system phenotypes.
BACKGROUND The pathophysiology of vasovagal syncope is poorly understood, and the treatment usually ineffective. Our clinical experience is that patients with vasovagal syncope fall into 2 groups, based on their supine systolic blood pressure, which is either normal (>100 mm Hg) or low (70-100 mm Hg). We investigated neural circulatory control in these 2 phenotypes. METHODS AND RESULTS Sympat...
متن کاملRecurrent Postural Vasovagal Syncope
Background—The pathophysiology of vasovagal syncope is poorly understood, and the treatment usually ineffective. Our clinical experience is that patients with vasovagal syncope fall into 2 groups, based on their supine systolic blood pressure, which is either normal ( 100 mm Hg) or low (70–100 mm Hg). We investigated neural circulatory control in these 2 phenotypes. Methods and Results—Sympathe...
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Vaddadi and co-workers, from the Baker Heart and Diabetes Research Institute of Melbourne, have examined, in a group of patients with a clinical history of recurrent postural vasovagal syncope, the behaviour of efferent postganglionic muscle sympathetic nerve traffic, directly assessed via the microneurographic technique in the peroneal nerve, during a fainting episode triggered by tilting. The...
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Syncope is defined as a transient loss of consciousness and postural tone, characterized by rapid onset, short duration, and spontaneous recovery, and the process of syncope progression is here described with two types of sympathetic change. Simultaneous recordings of microneurographically-recorded muscle sympathetic nerve activity (MSNA) and continuous and noninvasive blood pressure measuremen...
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Orthostatic intolerance is the inability to tolerate the upright posture and is relieved by recumbence. It most commonly affects young women and has a major impact on quality of life and psychosocial well-being. Several forms of orthostatic intolerance have been described. The most common one is the recurrent vasovagal syncope (VVS) phenotype which presents as a transient and abrupt loss of con...
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